Phosphodiesterases link the aryl hydrocarbon receptor complex to cyclic nucleotide signaling
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چکیده
منابع مشابه
Phosphodiesterases link the aryl hydrocarbon receptor complex to cyclic nucleotide signaling.
The aryl hydrocarbon receptor (AHR) is a major transcription factor regulated by different mechanisms. The classical view of AHR activation by xenobiotics needs to be amended by recent findings on the regulation of AHR by endogenous ligands and by crosstalk with other signaling pathways. In the cytosol the AHR recruits a large number of binding partners, including HSP90, p23, XAP2 and the ubiqu...
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ژورنال
عنوان ژورنال: Biochemical Pharmacology
سال: 2009
ISSN: 0006-2952
DOI: 10.1016/j.bcp.2008.08.027